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Bisco TheraCal LC Syringe
  • Bisco TheraCal LC Box Resin-Modified Calcium Silicate Pulp Protectant/Liner
  • Bisco TheraCal LC Syringe

TheraCal LC®

TheraCal LC is a light-cured, resin-modified calcium silicate. Its unique apatite stimulating ability makes it ideal for direct and indirect pulp capping and as a protective liner.

Item No:
Dental Advisor Clinical Problem Solver 2022 Dental Advisor Top Pulpal Protectant 2023 Dental Advisor Top Pulpal Protectant 2022 2021 Dental Advisor TheraCal LC Dental Advisor Top Pulpal Protectant 2020 Dental Advisor Top Pulpal Protectant 2019 Dental Advisor Top Pulpal Protectant 2018 Dental Advisor Top Pulpal Protectant 2017 Townie Choice Award 2016 Dental Advisor Top Pulpal Protectant/Liner 2016 Dental Advisor Top Pulpal Protectant/Liner 2015 Dental Advisor Top Pulpal Protectant/Liner 2014 Editors’ Choice Dental Advisor 5.0 Rating Dental Product Shopper Recommended Product


Resin-Modified Calcium Silicate Pulp Protectant/Liner
TheraCal LC is a light-cured, resin-modified calcium silicate filled liner designed for use in direct and indirect pulp capping and as a protective liner under composites, amalgams, cements, and other base materials. It can be used as an alternative to calcium hydroxide, glass ionomer, RMGI, IRM/ZOE and other restorative materials. TheraCal LC performs as a barrier and protectant of the dental pulpal complex.

TheraCal LC’s precise placement allows its use in all deep cavity preparations. The light-cured set permits immediate placement and condensation of the restorative material. Its proprietary formulation allows for a command set with a light curing unit while maintaining ease of placement due to thixotropic properties. The proprietary hydrophilic resin formulation creates a stable and durable liner.

Unique Benefits:

  • Calcium release stimulates1* hydroxyapatite and secondary dentin bridge formation2,3
  • Alkaline pH promotes healing and apatite formation2,4
  • Significant calcium release1 leads to protective seal5,7,8
  • Protects and insulates the pulp5,6
  • Moisture tolerant1 and radiopaque – can be placed under restorative materials and cements

Clinical Significance:

  • The proprietary formulation of TheraCal LC consists of tri-calcium silicate particles in a hydrophilic monomer that provides significant calcium release* making it a uniquely stable and durable material as a liner or base
TheraCal LC®

Features & Benefits

Pulp Capping Agent

Pulp Capping Agent

Designed for use in direct and indirect pulp capping.

Protective Liner

Protective Liner

Performs as an ideal protective liner under composites, amalgams, cements, and other base materials.

Protective Seal

Protective Seal

Significant calcium release1** leads to protective seal.5,7,8

Calcium Release

Calcium Release

Calcium release stimulates1* hydroxyapatite and secondary bridge formation.2,3

Alkaline pH

Alkaline pH

Alkaline pH promotes pulp vitality.4



Forms a protective barrier to protect the pulp from thermal changes.5,6



Visible on radiographs to easily distinguish caries.



Light cured material, which permits immediate placement of restorative material.



Can be used with all etch techniques (self-, selective-, and total-etch) for optimal bonding and finishing of the restoration.

Moisture Tolerant

Moisture Tolerant

Moisture Tolerant1 Unlike calcium hydroxide, TheraCal LC has low solubility and will not wash out over time.

Easy Syringe Application

Easy Syringe Application

Easy and fast syringe delivery offers controlled and precise placement. Material is easy to manipulate without dripping or slumping.

Time Saver

Time Saver

Can be directly applied to the pulp exposure and be used as a liner in the same prep, with no need for two separate products.


“TheraCal LC has been an integral part of my pulp capping procedures for over 7 years and I have come to trust its consistent reliability to keep nerves calm.”
  - Mark Malterud, DDS

The Restorative Touch of TheraCal LC
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BISCO's TheraFamily: The Leaders in Resin-Modified Calcium Silicate
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Repair Amalgam Restorations with Recurrent Caries
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Protecting the Pulp with Less Sensitivity
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A Go-To Material for Protecting the Pulp
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TheraCal LC - A Reliable Material that Protects the Pulp
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Re-treating a Tooth with Deep Caries
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Solving Clinical Challenges with Calcium-Releasing Products
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Restorative Solutions
Meet the Award-Winning Thera Family
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One Practice, Two Dentists
A Day in the Life with BISCO's Dream Team
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Revitalization and Restoration Following Deep Caries
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BISCO's growing family of calcium-releasing materials
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What is all the Hype About Calcium Releasing Materials
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Dental Product Shopper Evaluator's Choice Award 2019
The Science of Restorative Dentistry
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Treatment of Deep Caries of Tooth No. 9 in Adolescent
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Evaluators' Choice 2018 Awarded to TheraCal LC
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New Filler Technology Leads to Clinical Breakthrough
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3 Ways Pulp Cap Breakthroughs are Making Patient's - and Dentist's - Lives Better
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Treating Dental Trauma
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TheraCal LC Three-year Clinical Performance Report
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To submit a question regarding BISCO products, please click here.

What are the differences and similarities between TheraCal LC and Mineral Trioxide Aggregate (MTA) material?
TheraCal LC is a resin-modified calcium tri-silicate that has enhanced physical properties when compared to MTA material. Essentially, the primary chemical used in both materials are similar (Portland cement) but TheraCal LC contains a patent pending hydrophilic resin, which allows for immediate light curing and facilitates calcium release. Similar to MTA material, TheraCal LC promotes healing due to the alkaline pH, and the calcium release assists in the formation of dentin bridge.

What is the difference between TheraCal LC and Calcium Hydroxide
Calcium hydroxide is the primary chemical contained in many dentin liners and pulp capping agents. One of the known limitations of calcium hydroxide-based materials is their relatively high solubility, which leads to dissolution of the material over time. 

Do I need to bond before placing TheraCal LC?
Bonding is not required or recommended before placement of TheraCal LC on dentin. TheraCal LC allows the maximum amount of calcium release. 

I am using RMGI for liners and pulp-capping; why should I switch?
TheraCal LC promotes hydroxyl-apatite formation through ion/water exchange with the tooth structure. Resin-modified glass ionomers are unable to promote hydroxyl-apatite formation and have been shown to be cytotoxic to the pulpal complex.  Due to the inclusion of polyacrylic acid, RMGI’s may actually inhibit apatite formation.

What can I use TheraCal LC for?
TheraCal LC can be used as a liner under all restorative materials. It can also be used as a direct or indirect pulp-capping agent.

Will TheraCal LC wash out over time?
No, TheraCal LC is virtually insoluble when compared to other traditional calcium hydroxide-based liners and pulp-capping agents.

Can TheraCal LC be used in pediatric cases for either direct or indirect pulp capping?
Yes. TheraCal LC is indicated for both direct and indirect pulp capping, and can be used safely with pediatric patients. TheraCal LC will provide pulpal protection and decrease the risk of post-operative sensitivity in cases where deep preparations are needed, or where carious or mechanical exposures occur. The ability to light-cure the material will allow for faster working time as well, which may be helpful when dealing with younger patients.

What role does TheraCal LC’s Unique Hydrophilic Matrix play in its composition?
BISCO has developed a unique hydrophilic matrix that allows for ion exchange. Previous or traditional resin matrices have been hydrophobic, but BISCO’s matrix allows for ion exchange as water flows into the matrix, reacts, and calcium hydroxide ions are released. The matrix is hydrophilic but will not dissolve over time.



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* Bisco has, on file, the calcium release data for TheraCal LC.
1. Gandolfi MG, Siboni F, Prati C. Chemical-physical properties of TheraCal, a novel light-curable MTA-like material for pulp capping . International Endodontic Journal. 2012 Jun;45(6):571-9.
2. ADA definitions for direct and indirect pulp capping at:
3. Apatite-forming Ability of TheraCal Pulp-Capping Material, M.G. GANDOLFI, F. SIBONI, P. TADDEI, E. MODENA, and C. PRATI J Dent Res 90 (Spec Iss A):abstract number 2520, 2011 (
4. Okabe T, Sakamoto M, Takeuchi H, Matsushima K (2006) Effects of pH on mineralization ability of human dental pulp cells. Journal of Endodontics 32, 198-201.
5. Sangwan P; Sangwan A; Duhan J; Rohilla A. Tertiary dentinogenesis with calcium hydroxide: a review of proposed mechanisms. Int Endod J. 2013; 46(1):3-19
6. Selcuk SAVAS, Murat S. BOTSALI, Ebru KUCUKYILMAZ, Tugrul SARI. Evaluation of temperature changes in the pulp chamber during polymerization of light-cured pulp-capping materials by using a VALO LED light curing unit at different curing distances. Dent Mater J. 2014;33(6):764-9.
7. Cantekin K. Bond strength of different restorative materials to light-curable mineral trioxide aggregate. J Clin Pediatr Dent. 2015 Winter;39(2):143-8.
8. Mechanical Properties of New Dental Pulp-Capping Materials Over Time. M. NIELSEN, R. VANDERWEELE, J. CASEY, and K. VANDEWALLE, USAF, JBSA-Lackland, TX, , J Dent Res 93(Spec Iss A): 495, 2014 (