Yes, dentin should always be cleaned prior to bonding.
If using an Total Etch (Etch-and-Rinse) adhesive, using a Bisco etchant with BAC (Benzalkonium Chloride) eliminates the need for a separate antimicrobial agent.
If using a Self-Etch adhesive, application of an antimicrobial such as 2% Chlorhexidine or glutaraldehyde containing solutions will disinfect the dentin, and may also inhibit MMPs, which is still yet to be proven in vivo. MMPs are Matrix Metallo-Proteinases, inactive enzymes in dentin that are activated by acid, which may degrade the hybrid layer over time. MMPs are inhibited by endogenous inhibitors, such as 2% Chlorhexidine or BAC (benzalkonium chloride).
More important is selecting a hydrophobic adhesive which minimizes water content and is less acidic (pH > 3).